Newer systems, like nanoparticles, may have a complex in vivo biology. If you need to explore the PK and PD aspects of your product we are here to help.
We are specialized in non-linear kinetics and indirect dynamics.
We offer consulting services based on SAAM II or MATLAB.
Example of project we consulted. To explain the long-acting kinetics of a PLGA reformulated TAF for very long-acting prevention, we created a model in SAAM2 representing the injection kinetics in rodents. The model was then suitable for designing primate experiments with much more confidence.
Perazzolo et al, Frontiers Pharma, 2020