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Physiologically based Pharmacokinetic Model Validated to Enable Predictions Of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products
https://pubmed.ncbi.nlm.nih.gov/38382809/
February 20, 2024
Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213455/abstract
September 01, 2023
A novel formulation enabled transformation of 3 HIVdrugs tenofovir-lamivudine-dolutegravir (TLD) from short-acting to long-acting all-in-one injectable
https://journals.lww.com/aidsonline/abstract/9900/a_novel_formulation_enabled_transformation_of_3.333.aspx#
August 25, 2023
SAAM II: Selected Software Use Cases in Modern PK-PD Data Analysis
https://www.page-meeting.org/pdf_assets/10670-abstract.pdf
July 2023
AAPSNEWSMAGAZINE
Emerging Role of Systems Pharmacology, Long-acting, & Targeted Drug-combination Tech in Making Therapeutic & Health Impact
https://www.aapsnewsmagazine.org/
October 2022
J Pharm Sci
Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 2: Model for the Drug-combination Nanoparticles.
https://www.sciencedirect.com/science/article/pii/S0022354921005529?dgcid=coauthor
January 31th, 2022
J Pharm Sci
Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture
https://www.sciencedirect.com/science/article/abs/pii/S0022354921005475?dgcid=coauthor
December 9th, 2021
J Pharm Sci
Systems and Clinical Pharmacology of COVID-19 Therapeutic Candidates
https://www.sciencedirect.com/science/article/pii/S0022354920307486
January 15th, 2021
Frontiers in Pharmacology
Bictegravir Plus Tenofovir Alafenamide Nanoformulation as a Long-Acting Pre-Exposure Prophylaxis Regimen: Application of Modeling to Design Non-Human Primate Pharmacokinetic Experiments
https://www.frontiersin.org/articles/10.3389/fphar.2020.603242/full
January 15th, 2021
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